Glucocorticoid Receptor-mediated transactivation is hampered by Striatin-3, a novel interaction partner of the receptor

Abstract The transcriptional activity of the glucocorticoid receptor (GR) is co-determined by its ability to recruit a vast and varying number of cofactors. We here identify Striatin-3 (STRN3) as a novel interaction partner of GR that interferes with GR’s ligand-dependent transactivation capacity. R...

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Detalhes bibliográficos

Principais autores:	Ioanna Petta, Nadia Bougarne, Jolien Vandewalle, Lien Dejager, Sofie Vandevyver, Marlies Ballegeer, Sofie Desmet, Jonathan Thommis, Lode De Cauwer, Sam Lievens, Claude Libert, Jan Tavernier, Karolien De Bosscher
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Nature Portfolio 2017-08-01
coleção:	Scientific Reports
Acesso em linha:	https://doi.org/10.1038/s41598-017-09246-6
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