Modification of Lhx2 activity for ex vivo amplification of human iPSC-derived hematopoietic stem/progenitor cells

Hematopoietic stem cells (HSCs) obtained from patient-derived human induced pluripotent stem cells (iPSCs) are a promising tool for curing various hematological disorders. We previously demonstrated that enforced expression of the LIM-homeobox transcription factor Lhx2, which is essential for mouse...

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Номзүйн дэлгэрэнгүй

Үндсэн зохиолчид:	Kenji Kitajima, Yuna Takahashi, Hikaru Ando, Minako Shingai, Mako Hamasaki, Miyu Tanikawa, Mai Kanokoda, Marino Nakajima, Yasumasa Nishito, Takahiko Hara
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	Frontiers Media S.A. 2024-10-01
Цуврал:	Frontiers in Cell and Developmental Biology
Нөхцлүүд:	iPSCs HSPCs organoid differentiation Lhx2 homeobox
Онлайн хандалт:	https://www.frontiersin.org/articles/10.3389/fcell.2024.1482989/full
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!