Exploration of the Possible Relationships Between Gut and Hypothalamic Inflammation and Allopregnanolone: Preclinical Findings in a Post-Finasteride Rat Model

Background: Finasteride, a 5α-reductase inhibitor commonly prescribed for androgenetic alopecia, has been linked to persistent adverse effects after discontinuation, known as post-finasteride syndrome (PFS). Symptoms include neurological, psychiatric, sexual, and gastrointestinal disturbances. Emerg...

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Autores principales:	Silvia Diviccaro, Roberto Oleari, Federica Amoruso, Fabrizio Fontana, Lucia Cioffi, Gabriela Chrostek, Vera Abenante, Jacopo Troisi, Anna Cariboni, Silvia Giatti, Roberto Cosimo Melcangi
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	MDPI AG 2025-07-01
Colección:	Biomolecules
Materias:	intestinal macrophages NF-κB PPAR-α PPAR-γ acetate butyrate
Acceso en línea:	https://www.mdpi.com/2218-273X/15/7/1044
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!