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Biological impact of mutually exclusive exon switching.

Alternative splicing can expand the diversity of proteomes. Homologous mutually exclusive exons (MXEs) originate from the same ancestral exon and result in polypeptides with similar structural properties but altered sequence. Why would some genes switch homologous exons and what are their biological...

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Bibliografske podrobnosti
Principais autores: Su Datt Lam, M Madan Babu, Jonathan Lees, Christine A Orengo
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science (PLoS) 2021-03-01
Serija:PLoS Computational Biology
Online dostop:https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1008708&type=printable
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