Fallopian tube secreted protein affects ovarian metabolites in high grade serous ovarian cancer

High grade serous ovarian cancer (HGSOC), the most lethal histotype of ovarian cancer, frequently arises from fallopian tube epithelial cells (FTE). Once transformed, tumorigenic FTE often migrate specifically to the ovary, completing the crucial primary metastatic step and allowing the formation of...

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Bibliografiske detaljer

Principais autores:	Tova M. Bergsten, Sarah E. Levy, Katherine E. Zink, Hannah J. Lusk, Melissa R. Pergande, Stephanie M. Cologna, Joanna E. Burdette, Laura M. Sanchez
Format:	Artigo
Sprog:	Inglês
Udgivet:	Frontiers Media S.A. 2022-11-01
Serier:	Frontiers in Cell and Developmental Biology
Fag:	ovarian cancer imaging mass spectrometry (IMS) fallopian tube tumor micro environment proteomics SPARC
Online adgang:	https://www.frontiersin.org/articles/10.3389/fcell.2022.1042734/full
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