Mechanisms, efficacy, and future perspectives of cellular-based therapies for liver fibrosis/cirrhosis: focusing on mesenchymal stromal cells

Abstract Liver fibrosis/cirrhosis, characterized by excessive deposition of extracellular matrix (ECM) and formation of fibrous scars, arises from chronic liver injury and poses a significant global health burden. Although liver transplantation remains the sole curative option, its application is li...

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Detalhes bibliográficos

Principais autores:	Xuan Pan, Tianyun Gao, Bin Wang
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2025-12-01
coleção:	Cell & Bioscience
Assuntos:	Cell therapy Mesenchymal stromal cells Liver fibrosis/cirrhosis Mechanisms Clinical trials Immunomodulation
Acesso em linha:	https://doi.org/10.1186/s13578-025-01520-9
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