Refining the Sox10Dom/+ mouse model: A new breeding strategy with relevance to Hirschsprung disease genetics

Abstract Background The traditional Sox10Dom/+ mouse breeding strategy is costly and time‐consuming, so this study aims to optimize the breeding method and improve the scientific research efficiency. Methods We select the offspring from mating B6C3Fe Sox10Dom/+ male mice with C57BL/6J female mice, a...

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Hlavní autoři:	Chaoting Lan, Jiazhang Chen, Shenwei Huang, Yide Mu, Qiuhua Wang, Xin Zhong, Ning Tang, Xinying Zhao, Jieting Lu, Yuxin Wu, Lihua Huang, Jixiao Zeng, Wei Zhong, Yu Ouyang, Qiuming He, Yan Zhang
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Wiley 2025-10-01
Edice:	Animal Models and Experimental Medicine
Témata:	B6C3Fe6 B6C3Fe‐g Hirschsprung disease Sox10
On-line přístup:	https://doi.org/10.1002/ame2.70091
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