Activation of glial cells induces proinflammatory properties in brain capillary endothelial cells in vitro

Abstract Neurodegenerative diseases are often accompanied by neuroinflammation and impairment of the blood-brain barrier (BBB) mediated by activated glial cells through their release of proinflammatory molecules. To study the effects of glial cells on mouse brain endothelial cells (mBECs), we develo...

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Autori principali:	Annette Burkhart, Steinunn Sara Helgudóttir, Yahye A. Mahamed, Mikkel B. Fruergaard, Julie N. Holm-Jacobsen, Hulda Haraldsdóttir, Sara E. Dahl, Freja Pretzmann, Lisa Greve Routhe, Kate Lambertsen, Torben Moos, Maj Schneider Thomsen
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Nature Portfolio 2024-11-01
Serie:	Scientific Reports
Soggetti:	Blood-brain barrier Neuroinflammation In-vitro BBB model Glial cells Lipopolysaccharide
Accesso online:	https://doi.org/10.1038/s41598-024-78204-w
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