Mitochondria Targeted Antioxidant Significantly Alleviates Preeclampsia Caused by 11β-HSD2 Dysfunction via OPA1 and MtDNA Maintenance

We have previously demonstrated that placental 11β-hydroxysteroid dehydrogenase type 2 (11β-HSD2) dysfunction contributes to PE pathogenesis. We sought to elucidate molecular mechanisms underlying 11β-HSD2 dysfunction-induced PE and to seek potential therapeutic targets using a 11β-HSD2 dysfunction-...

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Bibliografski detalji

Glavni autori:	Jing Long, Yan Huang, Zhengshan Tang, Yali Shan, Dou Feng, Wenqin Wang, Juan Liu, Ying Huang, Hang Gu, Dewei Guo, Ruojin Yao, Xin Ni
Format:	Artigo
Jezik:	Inglês
Izdano:	MDPI AG 2022-07-01
Serija:	Antioxidants
Teme:	preeclampsia mitochondria placenta OXPHOS mtDNA
Online pristup:	https://www.mdpi.com/2076-3921/11/8/1505
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