IGF-I, IGF-II and insulin stimulate different gene expression responses through binding to the IGF-I receptor.
Insulin and the insulin-like growth factors (IGF)-I and –II are closely related peptides important for regulation of metabolism, growth, differentiation and development. The IGFs exert their main effects through the IGF-I receptor. Although the insulin receptor is the main physiological receptor for...
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| Principais autores: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2013-08-01
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| coleção: | Frontiers in Endocrinology |
| Assuntos: | |
| Acesso em linha: | http://journal.frontiersin.org/Journal/10.3389/fendo.2013.00098/full |
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