Efficient Preparation of α-Ketoacetals
The Weinreb amides 2a,b were prepared from the α,α-dimethoxyacetic acids 1c,d. A number of representative nucleophilic additions (RMgX and RLi) on 2 afforded α-ketoacetals 3a–j in 70–99% yield. These compounds represent a versatile arrangement of functi...
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| Hoofdauteurs: | , , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
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MDPI AG
2012-11-01
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| Reeks: | Molecules |
| Onderwerpen: | |
| Online toegang: | http://www.mdpi.com/1420-3049/17/12/13864 |
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