Metabolites and lipid species mediate the associations of adiposity in childhood and early adulthood with mammographic breast density in premenopausal women

Abstract Background Mammographic breast density (MBD), a strong predictor of breast cancer, is highly influenced by body mass index (BMI) in childhood and early adulthood, but the mechanisms underlying these associations are not fully understood. Our goal is to identify biomarkers that mediate the a...

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Autori principali:	Kayla R. Getz, Myung Sik Jeon, Lili Liu, Lei Liu, Haixiang Zhang, Chongliang Luo, Jingqin Luo, Adetunji T. Toriola
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	BMC 2025-02-01
Serie:	Breast Cancer Research
Soggetti:	Early-life Age 10 Age 18 Body mass index Lipidomics Mammographic breast density
Accesso online:	https://doi.org/10.1186/s13058-025-01970-6
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