From indigenous screening to pilot fermentation: comprehensive characterization of Bacillus subtilis YZ01 as a novel food-grade probiotic candidate

Bacillus subtilis YZ01, a novel strain isolated from the feces of a healthy individual, demonstrated potent in vitro biodegradation of uric acid (54.13%) and nucleosides (41.21%). Phylogenomic analysis of 2,198 single-copy orthologous genes confirmed strain YZ01’s taxonomic identity, while genome mi...

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Hauptverfasser:	Xiaoyu Cao, Yu Zhang, Qianqian Xu, Hai Yan
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Frontiers Media S.A. 2025-08-01
Schriftenreihe:	Frontiers in Microbiology
Schlagworte:	Bacillus subtilis probiotics safety assessment pilot-scale fermentation biodegradation
Online-Zugang:	https://www.frontiersin.org/articles/10.3389/fmicb.2025.1624208/full
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