Novel roles for HMGA2 isoforms in regulating oxidative stress and sensitizing to RSL3-Induced ferroptosis in prostate cancer cells

Oxidative stress is increased in several cancers including prostate cancer, and is currently being exploited in cancer therapy to induce ferroptosis, a novel nonapoptotic form of cell death. High mobility group A2 (HMGA2), a non-histone protein up-regulated in several cancers, can be truncated due t...

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Autores principales:	Taaliah Campbell, Ohuod Hawsawi, Veronica Henderson, Precious Dike, Bor-Jang Hwang, Yusuf Liadi, ElShaddai Z. White, Jin Zou, GuangDi Wang, Qiang Zhang, Nathan Bowen, Derrick Scott, Cimona V. Hinton, Valerie Odero-Marah
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Elsevier 2023-04-01
Colección:	Heliyon
Materias:	HMGA2 Truncated HMGA2 Oxidative stress Ferroptosis Prostate cancer
Acceso en línea:	http://www.sciencedirect.com/science/article/pii/S2405844023020170
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