Sirtuin 6 mediates the therapeutic effect of endometrial regenerative cell-derived exosomes in alleviation of acute transplant rejection by weakening c-myc-dependent glutaminolysis

BackgroundDespite the rapid development of immunosuppressive drugs, acute rejection (AR) remains a cause of allograft dysfunction and allograft failure. Although endometrial regenerative cell-derived exosomes (ERC-Exos) effectively alleviate AR, more research is required to fully understand the unde...

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Автори:	Tong Liu, Chenglu Sun, Xu Liu, Pengyu Zhao, Bo Shao, Yini Xu, Yiyi Xiao, Hongda Wang, Qiang Chen, Guangmei Yang, Hao Wang
Формат:	Artigo
Мова:	Inglês
Опубліковано:	Frontiers Media S.A. 2025-09-01
Серія:	Frontiers in Cell and Developmental Biology
Предмети:	endometrial regenerative cells exosomes SIRT6 CD4 + T cell differentiation glutaminolysis acute rejection
Онлайн доступ:	https://www.frontiersin.org/articles/10.3389/fcell.2025.1564382/full
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