Cbl-b negatively regulates TLR/MyD88-mediated anti-Toxoplasma gondii immunity

ABSTRACT Toxoplasma gondii is an important intracellular protozoan, which needs to exploit host nutrition for successful parasitism. We previously reported that Casitas B-lineage lymphoma-b (Cbl-b) was screened as a host dependency factor of T. gondii by using lentiviral CRISPR-Cas9-single guide RNA...

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Principais autores:	Haixia Wei, Shuizhen Wu, Liying Mai, Lili Yang, Weihao Zou, Hongjuan Peng
Formato:	Artigo
Idioma:	Inglês
Publicado:	American Society for Microbiology 2023-12-01
Series:	Microbiology Spectrum
Assuntos:	Toxoplasma gondii TLRs/MyD88 Cbl-b ubiquitination
Acceso en liña:	https://journals.asm.org/doi/10.1128/spectrum.00074-23
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