Voltage-Gated Ca2+ Channels in Dopaminergic Substantia Nigra Neurons: Therapeutic Targets for Neuroprotection in Parkinson's Disease?

The loss of dopamine (DA)-producing neurons in the substantia nigra pars compacta (SN) underlies the core motor symptoms of the progressive movement disorder Parkinson's disease (PD). To date, no treatment to prevent or slow SN DA neurodegeneration exists; thus, the identification of the underlying...

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Detalles Bibliográficos

Autor Principal:	Nadine J. Ortner
Formato:	Artigo
Idioma:	Inglês
Publicado:	Frontiers Media S.A. 2021-02-01
Series:	Frontiers in Synaptic Neuroscience
Assuntos:	voltage-gated Ca2+ channels Parkinson's disease Ca2+ oscillations Ca2+ channel blockers L-type Ca2+ channels R-type Ca2+ channels
Acceso en liña:	https://www.frontiersin.org/articles/10.3389/fnsyn.2021.636103/full
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