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Design of potent fluoro-substituted chalcones as antimicrobial agents

Owing to ever-increasing bacterial and fungal drug resistance, we attempted to develop novel antitubercular and antimicrobial agents. For this purpose, we developed some new fluorine-substituted chalcone analogs (3, 4, 9–15, and 20–23) using a structure–activity relationship approach. Target compoun...

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Hlavní autoři: Serdar Burmaoglu, Oztekin Algul, Arzu Gobek, Derya Aktas Anil, Mahmut Ulger, Busra Gul Erturk, Engin Kaplan, Aylin Dogen, Gönül Aslan
Médium: Artigo
Jazyk:Inglês
Vydáno: Taylor & Francis Group 2017-01-01
Edice:Journal of Enzyme Inhibition and Medicinal Chemistry
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On-line přístup:http://dx.doi.org/10.1080/14756366.2016.1265517
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