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Best Paper NASS 2013: Link-N can stimulate proteoglycan synthesis in the degenerated human intervertebral discs

Intervertebral disc (IVD) degeneration is the most common cause of back pain. Presently there is no medical treatment, leaving surgery as the only offered option. Here we evaluate the potential of Link-N to promote extracellular matrix regeneration in human IVDs. Human disc cells cultured in alginat...

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Principais autores: R Gawri, J Antoniou, J Ouellet, W Awwad, T Steffen, P Roughley, L Haglund, F Mwale
Format: Artigo
Sprog:Inglês
Udgivet: Forum Multimedia Publishing LLC 2013-09-01
Serier:European Cells & Materials
Fag:
Human intervertebral disc degeneration
regeneration
tissue engineering
organ culture
proteoglycans
bioactive peptides
Link-N
biological repair
Online adgang:http://www.ecmjournal.org/journal/papers/vol026/pdf/v026a08.pdf
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