VIRMA/IGF2BP3-mediated ANLN upregulation promotes intrahepatic cholangiocarcinoma growth by forming a positive feedback loop with RhoA/YAP1/TEAD1 signaling pathway

Abstract The prognosis of patients with intrahepatic cholangiocarcinoma (ICC) remains poor owing to the lack of effective targeted therapeutic strategies. Thus, the exploration of the molecular pathogenesis of ICC is urgently required. The cytoskeleton protein, anillin (ANLN), has been reported to c...

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Ngā kaituhi matua:	Jiajun Zhang, Ning Huang, Lin-rui Gao, Ai Guo, Hongming Deng, Liming Wang, Mei Liu
Hōputu:	Artigo
Reo:	Inglês
I whakaputaina:	Nature Publishing Group 2026-01-01
Rangatū:	Cell Death and Disease
Urunga tuihono:	https://doi.org/10.1038/s41419-025-08197-5
Ngā Tūtohu:	Tāpirihia he Tūtohu Kāore He Tūtohu, Me noho koe te mea tuatahi ki te tūtohu i tēnei pūkete!