Immunophenotypic skewing of B cells toward IgD⁻CD27⁻IgG⁺ subtype and metabolic attenuation in colorectal cancer

Abstract Colorectal cancer (CRC) is the third most prevalent cancer and understanding its tumor microenvironment (TME) is crucial for the development of innovative therapies. Despite the presence of B cells in CRC infiltrate, their clinical significance is poorly understood. In this study, we observ...

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Hlavní autoři:	Eleonora Martinis, Silvia Tonon, Viviana Valeri, Alessandra Colamatteo, Carolina Ricci, Caterina Trevisan, Eleonora Capezzali, Matteo Pivetta, Serena Battista, Marta Mozzon, Alessandro Uzzau, Giuseppe Matarese, Andrea Cossarizza, Barbara Frossi, Carlo Pucillo
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Nature Portfolio 2026-02-01
Edice:	Scientific Reports
On-line přístup:	https://doi.org/10.1038/s41598-026-41446-x
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