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Linking shox/shox2 deficiency with fgfr3 gain-of-function and natriuretic peptides

Short stature homeobox (SHOX) and its close paralogue SHOX2 are important transcriptional regulators of developmental processes. To understand how they function both individually and as an ensemble, we examined their mutual interdependence using zebrafish as a model. As both genes maintain important...

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Principais autores: Sandra Hoffmann, Sabrina Diebold, Ralph Roeth, Annette Löwen, Stefanie Mellein, Steffen Just, Gudrun A. Rappold
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2026-04-01
Series:Frontiers in Endocrinology
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Acceso en liña:https://www.frontiersin.org/articles/10.3389/fendo.2026.1803846/full
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