Discovery of 2′,6-Bis(4-hydroxybenzyl)-2-acetylcyclohexanone, a Novel FtsZ Inhibitor

Multi-drug resistance is increasing in the pathogenic bacterium <i>S. pneumoniae</i>, which is mainly responsible for meningitis and community-acquired pneumonia (CAP), highlighting the need for new anti-pneumococcal agents. We have identified a potential anti-pneumococcal agent, enol <b>3</b>, whic...

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Autors principals:	Hsuan-Yu J. Lin, Rachana Rao Battaje, Jinlong Tan, Munikumar Doddareddy, Hemendra Pal Singh Dhaked, Shalini Srivastava, Bryson A. Hawkins, Laith Mohammad Hilal Al-Shdifat, David E. Hibbs, Dulal Panda, Paul W. Groundwater
Format:	Artigo
Idioma:	Inglês
Publicat:	MDPI AG 2022-10-01
Col·lecció:	Molecules
Matèries:	cell division Z-ring FtsZ inhibitor chemical synthesis molecular docking
Accés en línia:	https://www.mdpi.com/1420-3049/27/20/6993
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