Kv1.3 palmitoylation regulates spatial distribution and channel removal from the immunological synapse
Abstract Kv1.3 is the main voltage-gated potassium channel in T cells. At the immunological synapse (IS), it sustains Ca2⁺ signaling and facilitates T cell activation. Aberrant Kv1.3 expression or activity is linked to autoimmune disorders, yet the mechanisms regulating its targeting and organizatio...
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| Principais autores: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer
2026-04-01
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| Colecção: | Cellular and Molecular Life Sciences |
| Assuntos: | |
| Acesso em linha: | https://doi.org/10.1007/s00018-026-06202-4 |
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