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Impact of Individual Viral Gene Segments from Influenza A/H5N8 Virus on the Protective Efficacy of Inactivated Subtype-Specific Influenza Vaccine

Since its emergence in 2014, the highly pathogenic avian influenza H5N8 virus has continuously and rapidly spread worldwide in the poultry sector resulting in huge economic losses. A typical inactivated H5N8 vaccine is prepared using the six internal genes from A/PR8/1934 (H1N1) and the two major an...

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Uloženo v:
Hlavní autoři: Yassmin Moatasim, Ahmed Kandeil, Ahmed Mostafa, Omnia Kutkat, Mohamed El Sayes, Ahmed N. El Taweel, Maha AlKhazindar, Elsayed T. AbdElSalam, Rabeh El-Shesheny, Ghazi Kayali, Mohamed A. Ali
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI AG 2021-03-01
Edice:Pathogens
Témata:
PR8-based influenza vaccine
innate immunity
humoral immunity
vaccine efficacy
H5N8
On-line přístup:https://www.mdpi.com/2076-0817/10/3/368
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