Myeloid neoplasms with PHF6 mutations: context-dependent genomic and prognostic characterization in 176 informative cases

Abstract Recent reports suggest a favorable prognosis for PHF6 mutation (PHF6 MUT) in chronic myelomonocytic leukemia (CMML) and unfavorable in acute myeloid leukemia (AML). We accessed 176 consecutive patients with a spectrum of myeloid neoplasms with PHF6 MUT, including AML (N = 67), CMML (N = 49)...

Ausführliche Beschreibung

Bibliografische Detailangaben

Hauptverfasser:	Saubia Fathima, Ali Alsugair, Rong He, Abhishek A. Mangaonkar, Kebede H. Begna, Animesh Pardanani, Cinthya J. Zepeda Mendoza, Kaaren K. Reichard, Naseema Gangat, Ayalew Tefferi
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Nature Publishing Group 2025-03-01
Schriftenreihe:	Blood Cancer Journal
Online-Zugang:	https://doi.org/10.1038/s41408-025-01231-x
Tags:	Tag hinzufügen Keine Tags, Fügen Sie das erste Tag hinzu!