Shared and distinct genetic etiologies for different types of clonal hematopoiesis

Abstract Clonal hematopoiesis (CH)—age-related expansion of mutated hematopoietic clones—can differ in frequency and cellular fitness by CH type (e.g., mutations in driver genes (CHIP), gains/losses and copy-neutral loss of chromosomal segments (mCAs), and loss of sex chromosomes). Co-occurring CH r...

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Detalles Bibliográficos

Principais autores:	Derek W. Brown, Liam D. Cato, Yajie Zhao, Satish K. Nandakumar, Erik L. Bao, Eugene J. Gardner, Aubrey K. Hubbard, Alexander DePaulis, Thomas Rehling, Lei Song, Kai Yu, Stephen J. Chanock, John R. B. Perry, Vijay G. Sankaran, Mitchell J. Machiela
Formato:	Artigo
Idioma:	Inglês
Publicado:	Nature Portfolio 2023-09-01
Series:	Nature Communications
Acceso en liña:	https://doi.org/10.1038/s41467-023-41315-5
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