Rif1 interacts with non-canonical polycomb repressive complex PRC1.6 to regulate mouse embryonic stem cells fate potential

Abstract Mouse embryonic stem cells (mESCs) cycle in and out of a transient 2-cell (2C)-like totipotent state, driven by a complex genetic circuit involves both the coding and repetitive sections of the genome. While a vast array of regulators, including the multi-functional protein Rif1, has been r...

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Hlavní autoři:	Lu Li, Pishun Li, Jiale Chen, Li Li, Yunfan Shen, Yangzixuan Zhu, Jiayi Liu, Lu Lv, Song Mao, Fang Chen, Guang Hu, Kai Yuan
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	SpringerOpen 2022-08-01
Edice:	Cell Regeneration
Témata:	2C-like Totipotency MERVL Rif1 PRC1.6
On-line přístup:	https://doi.org/10.1186/s13619-022-00124-9
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