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Short-term MRI measurements as predictors of EDSS progression in relapsing-remitting multiple sclerosis: grey matter atrophy but not lesions are predictive in a real-life setting

Background Magnetic resonance imaging (MRI) is the best biomarker of inflammatory disease activity in relapsing remitting Multiple Sclerosis (RRMS) so far but the association with disability is weak. Appearance of new MRI-lesions is used to evaluate response to immunotherapies in individual patients...

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Principais autores: Johanna von Gumberz, Mina Mahmoudi, Kim Young, Sven Schippling, Roland Martin, Christoph Heesen, Susanne Siemonsen, Jan-Patrick Stellmann
Format: Artigo
Sprog:Inglês
Udgivet: PeerJ Inc. 2016-09-01
Serier:PeerJ
Fag:
Multiple sclerosis
MRI
Disability progression
Predictors
Atrophy
Lesions
Online adgang:https://peerj.com/articles/2442.pdf
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