Aptamer-based nanotrains and nanoflowers as quinine delivery systems

In this study, we designed aptamer-based self-assemblies for the delivery of quinine. Two different architectures were designed by hybridizing quinine binding aptamers and aptamers targeting Plasmodium falciparum lactate dehydrogenase (PfLDH): nanotrains and nanoflowers. Nanotrains consisted in cont...

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Detalles Bibliográficos

Principais autores:	Mengyuan Cao, Anthony Vial, Laetitia Minder, Aurore Guédin, Sébastien Fribourg, Laurent Azéma, Cécile Feuillie, Michael Molinari, Carmelo Di Primo, Philippe Barthélémy, Leblond Chain Jeanne
Formato:	Artigo
Idioma:	Inglês
Publicado:	Elsevier 2023-12-01
Series:	International Journal of Pharmaceutics: X
Assuntos:	Nanotrain Nanoflower Targeted delivery DNA aptamer Quinine Malaria
Acceso en liña:	http://www.sciencedirect.com/science/article/pii/S2590156723000166
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