Activated platelets stimulate effector CD8+ T cells to enhance HNSCC immunotherapy efficacy

Abstract Programmed Death Receptor-1 (PD-1) is an immune checkpoint receptor expressed on the surface of T cells. Monoclonal antibodies targeting PD-1 and its ligand, PD-L1, are among the most widely utilized immune checkpoint inhibitors in cancer immunotherapy, dramatically improving the prognosis...

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Hlavní autoři:	Zhennan Yuan, Lunhua Guo, Yuheng Pang, Wenjing Wang, Yuefeng Shang, Chufei Xie, Cheng Qian, Ji Sun, Xiaohong Wu
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Springer 2025-05-01
Edice:	Discover Oncology
Témata:	HNSCC PD-1 CyTOF Platelet
On-line přístup:	https://doi.org/10.1007/s12672-025-02596-y
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