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Crystal structure of human protein N-terminal glutamine amidohydrolase, an initial component of the N-end rule pathway.

The N-end rule states that half-life of protein is determined by their N-terminal amino acid residue. N-terminal glutamine amidohydrolase (Ntaq) converts N-terminal glutamine to glutamate by eliminating the amine group and plays an essential role in the N-end rule pathway for protein degradation. He...

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Autori principali: Mi Seul Park, Eduard Bitto, Kyung Rok Kim, Craig A Bingman, Mitchell D Miller, Hyun-Jung Kim, Byung Woo Han, George N Phillips
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science (PLoS) 2014-01-01
Serie:PLoS ONE
Accesso online:http://europepmc.org/articles/PMC4214742?pdf=render
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