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Impact of Progerin Expression on Adipogenesis in Hutchinson—Gilford Progeria Skin-Derived Precursor Cells

Hutchinson–Gilford progeria syndrome (HGPS) is a segmental premature aging disease caused by a mutation in <i>LMNA</i>. The mutation generates a truncated and farnesylated form of prelamin A, called progerin. Affected individuals develop several features of normal aging, including lipodystrophy caus...

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Bibliografiske detaljer
Principais autores: Farah Najdi, Peter Krüger, Karima Djabali
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2021-06-01
Serier:Cells
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Online adgang:https://www.mdpi.com/2073-4409/10/7/1598
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