Competition between NBS1 and ATMIN Controls ATM Signaling Pathway Choice
Ataxia telangiectasia mutated (ATM) protein kinase activation by DNA double-strand breaks (DSBs) requires the Mre11-Rad50-NBS1 (MRN) complex, whereas ATM interactor (ATMIN) protein is required for ATM signaling induced by changes in chromatin structure. We show here that NBS1 and ATMIN proteins comp...
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| Hauptverfasser: | , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Elsevier
2012-12-01
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| Schriftenreihe: | Cell Reports |
| Online-Zugang: | http://www.sciencedirect.com/science/article/pii/S221112471200383X |
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