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Absence of Cold-Inducible RNA-Binding Protein (CIRP) Promotes Angiogenesis and Regeneration of Ischemic Tissue by Inducing M2-Like Macrophage Polarization

Cold-inducible RNA-binding protein (CIRP) is an intracellular RNA-chaperone and extracellular promoter of inflammation, which is increasingly expressed and released under conditions of hypoxia and cold stress. The functional relevance of CIRP for angiogenesis and regeneration of ischemic muscle tiss...

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Principais autores: Matthias Kübler, Sebastian Beck, Silvia Fischer, Philipp Götz, Konda Kumaraswami, Hellen Ishikawa-Ankerhold, Manuel Lasch, Elisabeth Deindl
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2021-04-01
Serier:Biomedicines
Fag:
angiogenesis
cold-inducible RNA-binding protein
CIRP
CIRBP
neutrophil extracellular traps
NETs
Online adgang:https://www.mdpi.com/2227-9059/9/4/395
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