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GRPR-Antagonists Carrying DOTAGA-Chelator via Positively Charged Linkers: Perspectives for Prostate Cancer Theranostics

Gastrin-releasing peptide receptor (GRPR)-antagonists have served as motifs in the development of theranostic radioligands for prostate cancer. Our efforts have been focused on the development of radiolabeled RM26 (H-DPhe<sup>6</sup>–Gln<sup>7</sup>–Trp<sup>8</sup>–Ala<sup>9</sup>–Val<sup>10</sup>–G...

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Principais autores: Karim Obeid, Panagiotis Kanellopoulos, Ayman Abouzayed, Adam Mattsson, Vladimir Tolmachev, Berthold A. Nock, Theodosia Maina, Anna Orlova
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2024-04-01
coleção:Pharmaceutics
Assuntos:
prostate cancer
GRPR
GRPR-antagonist
radiotheranostics
PC-3 cell/tumor
neprilysin
Acesso em linha:https://www.mdpi.com/1999-4923/16/4/513
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