Breast cancer metastasis to brain results in recruitment and activation of microglia through annexin-A1/formyl peptide receptor signaling

Abstract Background Despite advancements in therapies, brain metastasis in patients with triple negative subtype of breast cancer remains a therapeutic challenge. Activated microglia are often observed in close proximity to, or within, malignant tumor masses, suggesting a critical role that microgli...

Whakaahuatanga katoa

Ngā taipitopito rārangi puna kōrero

Ngā kaituhi matua:	Sok Lin Foo, Karishma Sachaphibulkij, Corinne L. Y. Lee, Gracemary L. R. Yap, Jianzhou Cui, Thiruma Arumugam, Lina H. K. Lim
Hōputu:	Artigo
Reo:	Inglês
I whakaputaina:	BMC 2022-04-01
Rangatū:	Breast Cancer Research
Ngā marau:	Annexin-A1 STAT3 FPR2 Microglia Brain metastasis Breast cancer
Urunga tuihono:	https://doi.org/10.1186/s13058-022-01514-2
Ngā Tūtohu:	Tāpirihia he Tūtohu Kāore He Tūtohu, Me noho koe te mea tuatahi ki te tūtohu i tēnei pūkete!