A phage-encoded sponge protein suppresses bacterial TIR-Caspase immune signaling

Abstract Triggering immune response through generation of signal molecules is a common immune strategy across all domains of life. In the bacterial type IV Thoeris anti-phage system, a Toll/interleukin-1 receptor (TIR)-domain protein produces adenosine 5’-diphosphate-cyclo[N7:1”]-ribose (N7-cADPR) a...

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Autori principali:	Yu Chen, Linlin Wei, Zhenhao Han, Ruiliang Zhao, Zhifeng Zeng, Yanqiu Liu, Piaoran Zhang, Keyi Tan, Yue Fan, Long Sheng, Hao Wang, Rafael Pinilla-Redondo, Yue Feng, Wenyuan Han
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Nature Portfolio 2026-04-01
Serie:	Nature Communications
Accesso online:	https://doi.org/10.1038/s41467-026-71527-4
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