Diverse autoinhibitory mechanisms of FIIND-containing proteins: Insight into regulation of NLRP1 and CARD8 inflammasome.

Function-to-find domain (FIIND)-containing proteins, including NLRP1 and CARD8, are vital components of the inflammasome signaling pathway, critical for the innate immune response. These proteins exist in various forms due to autoproteolysis within the FIIND domain, resulting in full-length (FL), cl...

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主要な著者:	Jingfan Zhou, Chengrong Liu, Xin Wang, Zhenshan Liu, Zizhen Ming, Yonggang Wang, Chunxia Wang, Qiming Liang
フォーマット:	Artigo
言語:	Inglês
出版事項:	Public Library of Science (PLoS) 2025-01-01
シリーズ:	PLoS Pathogens
オンライン･アクセス:	https://doi.org/10.1371/journal.ppat.1012877
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