Spatial mechanisms of quality control during chaperone-mediated assembly of the proteasome
Abstract Cellular protein degradation requires a complex molecular machine, the proteasome. To mitigate the fundamental challenge of assembling the 66-subunit proteasome, cells utilize dedicated chaperones to order subunit addition. However, recent evidence suggests that proteasome assembly is not s...
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| Autores principales: | , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Nature Portfolio
2025-04-01
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| Colección: | Nature Communications |
| Acceso en línea: | https://doi.org/10.1038/s41467-025-58703-8 |
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