Multi-dimensional decoding of the TSPO signal in animal models of neuroinflammation using fluorescence-conjugated DPA714

Abstract Neuroinflammation is a core pathological process in multiple central nervous system diseases. Although positron emission tomography (PET) targeting the translocator protein (TSPO) (e.g., ¹⁸F-DPA-714) is widely used for in vivo inflammatory imaging, the cellular heterogeneity and functional...

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Autors principals:	Huanhuan Song, Zhibao Zhu, Limei Xiao, Qiuping Zhao, Chun Li, Aowei Lv, Xintong Yu, Zhuyu Gao, Jie Lin, Youliang Wang, Yuanyuan Zhang, Lijie Zhang, Runyun Li, Shaobo Yao, Mengchao Cui, Yi Lin, Ying Fu, V. Wee Yong, Rui Li
Format:	Artigo
Idioma:	Inglês
Publicat:	BMC 2026-06-01
Col·lecció:	Journal of Neuroinflammation
Matèries:	Translocator protein (TSPO) Neuroinflammation TSPO imaging probe Microglia CSF1R
Accés en línia:	https://doi.org/10.1186/s12974-026-03829-9
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