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Experimental Induction of Intracranial Aneurysms in Rats: A New Model Utilizing a Genetic Modification within the EDNRA Gene

The rupture of an intracranial aneurysm (IA) leads to life-threatening subarachnoid hemorrhage. Aside from well-established risk factors, recently published genome-wide association studies of IA revealed the strong association of a common variant near the endothelin receptor type A (EDNRA) gene with...

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Wedi'i Gadw mewn:
Prif Awduron: Tim Lampmann, Valeri Borger, Jürgen Konczalla, Suzana Gispert, Georg Auburger, Hartmut Vatter, Erdem Güresir
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: MDPI AG 2022-09-01
Cyfres:Brain Sciences
Pynciau:
intracranial aneurysm
risk factors
EDNRA
endothelin
animal model
rat
Mynediad Ar-lein:https://www.mdpi.com/2076-3425/12/9/1239
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