Integrin α5 subunit is required for the tumor supportive role of fibroblasts in colorectal adenocarcinoma and serves as a potential stroma prognostic marker

The tumorigenesis of colorectal cancer (CRC) is a complicated process, involving interactions between cancer cells and the microenvironment. The role of α5 integrin subunit in CRC remains controversial, and previous studies mainly focused on cancer cells. Herein, we report an important role of α5 in...

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Hlavní autoři:	Ling Lu, Ruting Xie, Rong Wei, Chunmiao Cai, Dexi Bi, Dingzi Yin, Hu Liu, Jiayi Zheng, Youhua Zhang, Feifei Song, Yaohui Gao, Linhua Tan, Qing Wei, Huanlong Qin
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Wiley 2019-12-01
Edice:	Molecular Oncology
Témata:	colorectal adenocarcinoma fibroblasts tumor stroma α5 integrin subunit
On-line přístup:	https://doi.org/10.1002/1878-0261.12583
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