Dimerization of GAS2 mediates crosslinking of microtubules and F-actin

Abstract The spectraplakin family protein GAS2 was originally identified as a growth arrest-specific protein, and recent studies have revealed its involvement in multiple cellular processes. Its dual interaction with actin filaments and microtubules highlights its essential role in cytoskeletal orga...

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Главные авторы:	Jiancheng An, Tsuyoshi Imasaki, Akihiro Narita, Shinsuke Niwa, Ryohei Sasaki, Tsukasa Makino, Ryo Nitta, Masahide Kikkawa
Формат:	Artigo
Язык:	Inglês
Опубликовано:	Springer Nature 2025-04-01
Серии:	The EMBO Journal
Предметы:	GAS2 Microtubule Actin Spectraplakin Cryo-Electron Microscope
Online-ссылка:	https://doi.org/10.1038/s44318-025-00415-2
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