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The pivotal roles of TIA proteins in 5' splice-site selection of alu exons and across evolution.

More than 5% of alternatively spliced internal exons in the human genome are derived from Alu elements in a process termed exonization. Alus are comprised of two homologous arms separated by an internal polypyrimidine tract (PPT). In most exonizations, splice sites are selected from within the same...

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Autors principals: Nurit Gal-Mark, Schraga Schwartz, Oren Ram, Eduardo Eyras, Gil Ast
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science (PLoS) 2009-11-01
Col·lecció:PLoS Genetics
Accés en línia:http://europepmc.org/articles/PMC2766253?pdf=render
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