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Characterization of a Replication-Incompetent Pseudorabies Virus Mutant Lacking the Sole Immediate Early Gene IE180

ABSTRACT The alphaherpesvirus pseudorabies virus (PRV) encodes a single immediate early gene called IE180. The IE180 protein is a potent transcriptional activator of viral genes involved in DNA replication and RNA transcription. A PRV mutant with both copies of IE180 deleted was constructed 20 years...

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Bibliografiske detaljer
Principais autores: Brendan W. Wu, Esteban A. Engel, Lynn W. Enquist
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2014-12-01
Serier:mBio
Online adgang:https://journals.asm.org/doi/10.1128/mBio.01850-14
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