Therapy and biomarker dependent progression-free survival in infant sonic hedgehog medulloblastoma: a multi-national retrospective cohort studyResearch in context

Summary: Background: Medulloblastoma in infants (iMB; aged < 5 years) presents the challenge of achieving cure while minimising deleterious cranio-spinal irradiation (CSI)-associated late-effects. Non-randomised phase 2 studies have examined upfront CSI omission and chemotherapy intensification for...

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Hlavní autoři:	Stacey Richardson, Debbie Hicks, Melissa Gough, Ellie R. Butler, Dean Thompson, Jemma Castle, Stephen Crosier, Miguel Garcia-Ariza, Idoia Martín-Guerrero, Sabine L.A. Plasschaert, Franck Bourdeaut, Christelle Dufour, Julien Masliah-Planchon, Francesca Romana Buttarelli, Veronica Biassoni, Maura Massimino, Koichi Ichimura, Yonehiro Kanemura, Vijay Ramaswamy, Amar Gajjar, Marcel Kool, Andrey Korshunov, Stefan M. Pfister, Martin Mynarek, Stefan Rutkowski, Edward C. Schwalbe, Simon Bailey, Steven C. Clifford
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Elsevier 2026-06-01
Edice:	EClinicalMedicine
Témata:	Medulloblastoma Infant SHH Therapy Prognosis Biomarkers
On-line přístup:	http://www.sciencedirect.com/science/article/pii/S2589537026001616
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