Denosumab ameliorates muscle indices in Chinese osteoporosis patients through clinical and bioinformatic evidence of RANKL in sarcopenia

Summary: This study investigated the effects of denosumab on muscle parameters in Chinese patients with primary osteoporosis and explored potential mechanisms through bioinformatic analyses. In a clinical trial involving 103 patients, 12 months of denosumab treatment significantly improved bone mine...

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Bibliographic Details

Main Authors:	Shaotian Li, Shanshan Hu, Xiaoli Zheng, Xiong Ku, Jingfeng Zou, Andong Zhang, Guqiao Nie, Yiting Liu, Chunhui Tian, Mi Yan, Yilan Yin, Yun Liu, Jingjing Wan, Wei Tan, Wen Peng
Format:	Artigo
Language:	Inglês
Published:	Elsevier 2026-02-01
Series:	iScience
Subjects:	Health sciences
Online Access:	http://www.sciencedirect.com/science/article/pii/S2589004225027701
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