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Mutational pressure promotes release of public CD8+ T cell epitopes by proteasome from SARS-CoV-2 RBD of Omicron and its current lineages

Summary: The COVID-19 pandemic was the most dramatic in the newest history with nearly 7 million deaths and global impact on mankind. Here, we report binding index of 305 human leukocyte antigen (HLA) class I molecules from 18,771 unique haplotypes of 28,104 individuals to 821 peptides experimentall...

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Autores principales: Anna A. Kudriaeva, Ivan O. Butenko, George A. Saratov, Maxim Т. Ri, Yuliana A. Mokrushina, Alexey A. Bondarev, Alena S. Evpak, Ivan V. Smirnov, Daria S. Matyushkina, Alexander G. Gabibov, Vadim M. Govorun, Alexey A. Belogurov, Jr.
Formato: Artigo
Lenguaje:Inglês
Publicado: Elsevier 2025-03-01
Colección:iScience
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Acceso en línea:http://www.sciencedirect.com/science/article/pii/S2589004225001336
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