Beyond Amyloid: Evolutionary and Immune-Metabolic Perspectives on Alzheimer’s Disease

Alzheimer’s disease (AD) is increasingly recognized as a multifactorial and systems-level disorder that extends beyond the classical amyloid cascade hypothesis. Rather than dismissing established concepts such as tau pathology, synaptic dysfunction, vascular compromise, mitochondrial abnormalities,...

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Detalhes bibliográficos

Autor principal:	George B. Stefano
Formato:	Artigo
Idioma:	Inglês
Publicado em:	IMR Press 2026-06-01
coleção:	Frontiers in Bioscience-Landmark
Assuntos:	alzheimer’s disease amyloid-β innate immunity microbiome-gut-brain axis neuroinflammation mitochondrial dysfunction
Acesso em linha:	https://www.imrpress.com/journal/FBL/31/6/10.31083/FBL53859
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